In order of appearance:
| The Orphanage | 1st and 3rd Shows | 2nd and 4th Shows | |||
| MOLLY | Brianna Fortmuller | Gabby Brutman | |||
| PEPPER | Jamie Wiggins | Taylor Cason | |||
| DUFFY | Ali Gutierrez | Emily Gray | |||
| JULY | Allie Binder | Sarika Ramalingam | |||
| TESSIE | Ashley Bussell | Mikayla Schwalbe | |||
| ANNIE | Lauren Dorn | Sarah Tweed | |||
| KATE | Natalie Virga | Amanda Fassett | |||
| RUBY (All Shows) | Sophia Beck | ||||
| JOSIE (All Shows) | Vittoria Conforti | ||||
| PEARL (All Shows) | Carly Robinson | ||||
| MARJORIE (All Shows) | Natalie Rose | ||||
| DOTTIE (All Shows) | Lindsey Ryan | ||||
| MISS HANNIGAN | Lexi Aviles | ||||
| BUNDLES McCLOSKEY | Wyland Collins | ||||
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| ST. MARK’S PLACE | |||||
| ROSIE THE APPLE SELLER | Brianna Fishel | ||||
| DOGCATCHER #1 | Ben Palajac | ||||
| DOGCATCHER #2 | Jonathan Widin | ||||
| SANDY | TBD | ||||
| LIEUTENANT WARD | Christian Cantrell | ||||
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| HOOVERVILLE | |||||
| ARTIE | Jared DeBest | ||||
| MARY | Tina Nagy | ||||
| EDDIE | Wyland Collins | ||||
| FRED | Jake Rome | ||||
| STELLA | Rebecca Bailey | ||||
| BETTY | Grace Hummelberg | ||||
| SOPHIE | Paige Mills | ||||
| PEGGY | Mackensie Kohl | ||||
| IRIS | Crissy Gutierrez | ||||
| JANE | Lauren Lyons | ||||
| N.Y.C. POLICEWOMAN | Chloe Anderson | ||||
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| THE WARBUCKS MANSION | |||||
| GRACE FARRELL | Alexis Sawyer | ||||
| DRAKE | Jonathan Widin | ||||
| CECILLE | Shanna Brajevic | ||||
| MRS. GREER | Shira Strongin | ||||
| ANNETTE | Lauren Lyons | ||||
| MRS. PUGH | Rebecca Bailey | ||||
| SERVANTS | Yasmeen Anand | Lauren Merrell | |||
| Chloe Anderson | Paige Mills | ||||
| Brianna Fishel | Colleen Moore | ||||
| Crissy Gutierrez | Tina Nagy | ||||
| Grace Hummelberg | Taylor Webb | ||||
| Mackensie Kohl | Megan Winsor | ||||
| Sammi Maloney | |||||
| Christian Cantrell | Ben Palajac | ||||
| Wyland Collins | Jake Rome | ||||
| DADDY WARBUCKS | Matthew Matusiewicz | ||||
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| N.Y.C. | |||||
| TOUR GUIDE | Shira Strongin | ||||
| TOURISTS | Sophia Beck, Shanna Brajevic, Grace Hummelberg, Lindsey Ryan, Non-Pepper | ||||
| YANKEES FANS | Brianna Fishel, Mackensie Kohl, Carly Robinson, Non-July, Non-Tessie | ||||
| BRATTY CHILDREN | Natalie Rose, Non-Annie, Non-Molly | ||||
| MOMS OF BRATTY CHILDREN | Rebecca Bailey, Taylor Webb | ||||
| PICKPOCKETS | Jared DeBest, Anysa Wilson | ||||
| COPS | Christian Cantrell | Chloe Anderson | |||
| HOT DOG VENDOR | Tina Nagy | ||||
| NEWSPAPER BOY | Jonathan Widin (End of number only) |
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| BUSINESSMAN | Jake Rome | ||||
| SECRETARY | Yasmeen Anand | ||||
| SHOE SHINE BOY | Wyland Collins | ||||
| TAXI DRIVER | Ben Palajac | ||||
| ROCKETTES | Crissy Gutierrez, Lauren Lyons, Lauren Merrell, Megan Winsor | ||||
| USHERETTE | Sammi Maloney | ||||
| MOVIEGOERS | Vittoria Conforti, Colleen Moore, Non-Duffy, Non-Kate | ||||
| STAR-TO-BE | Paige Mills | ||||
| ANGRY WOMAN (Offstage Voice) |
Lexi Aviles | ||||
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| EASY STREET | |||||
| ROOSTER HANNIGAN | Jared DeBest | ||||
| LILY ST. REGIS | Anysa Wilson | ||||
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| THE NBC RADIO STUDIO | |||||
| SOUND EFFECTS MAN | Christian Cantrell | ||||
| BERT HEALY | Ben Palajac | ||||
| WACKY | Wyland Collins | ||||
| JIMMY JOHNSON | Jonathan Widin | ||||
| FRED McCRACKEN | Jake Rome | ||||
| RONNIE BOYLAN | Taylor Webb | ||||
| BONNIE BOYLAN | Lauren Merrell | ||||
| CONNIE BOYLAN | Megan Winsor | ||||
| NBC PAGES | Grace Hummelberg | ||||
| Tina Nagy | |||||
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| THE WHITE HOUSE | |||||
| PRESIDENT FRANKLIN DELANO ROOSEVELT | Jake Rome | ||||
| MRS. ELEANOR ROOSEVELT | Colleen Moore | ||||
| LOUIS HOWE | Christian Cantrell | ||||
| 4 PRESIDENTIAL AIDES | Yasmeen Anand | ||||
| Shanna Brajevic | |||||
| Lauren Lyons | |||||
| Ben Palajac | |||||
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